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Chronic Fluoxetine Treatment Induces Brain Region-Specific Upregulation of Genes Associated with BDNF-Induced Long-Term Potentiation

Several lines of evidence implicate BDNF in the pathogenesis of stress-induced depression and the delayed efficacy of antidepressant drugs. Antidepressant-induced upregulation of BDNF signaling is thought to promote adaptive neuronal plasticity through effects on gene expression, but the effector ge...

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Detalles Bibliográficos
Autores principales: Alme, Maria Nordheim, Wibrand, Karin, Dagestad, Grethe, Bramham, Clive R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248427/
https://www.ncbi.nlm.nih.gov/pubmed/18301726
http://dx.doi.org/10.1155/2007/26496