PORTAL: Pilot study on the safety and tolerance of preoperative melatonin application in patients undergoing major liver resection: a double-blind randomized placebo-controlled trial

BACKGROUND: Major surgical procedures facilitate systemic endotoxinemia and formation of free radicals with subsequent inflammatory changes that can influence the postoperative course. Experimental data suggest that preoperative supraphysiological doses of melatonin, a potent immuno-modulator and an...

Descripción completa

Detalles Bibliográficos
Autores principales: Schemmer, Peter, Nickkholgh, Arash, Schneider, Heinz, Sobirey, Michael, Weigand, Markus, Koch, Moritz, Weitz, Jürgen, Büchler, Markus W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248566/
https://www.ncbi.nlm.nih.gov/pubmed/18215253
http://dx.doi.org/10.1186/1471-2482-8-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248566/
https://www.ncbi.nlm.nih.gov/pubmed/18215253
http://dx.doi.org/10.1186/1471-2482-8-2

Ejemplares similares