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Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A(2 )by affinity binding studies and molecular bioinformatics

BACKGROUND: The snake venom group IIA secreted phospholipases A(2 )(SVPLA(2)), present in the Viperidae snake family exhibit a wide range of toxic and pharmacological effects. They exert their different functions by catalyzing the hydrolysis of phospholipids (PL) at the membrane/water interface and...

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Detalles Bibliográficos
Autores principales: Faure, Grazyna, Gowda, Veerabasappa T, Maroun, Rachid C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248580/
https://www.ncbi.nlm.nih.gov/pubmed/18062812
http://dx.doi.org/10.1186/1472-6807-7-82