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Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A(2 )by affinity binding studies and molecular bioinformatics
BACKGROUND: The snake venom group IIA secreted phospholipases A(2 )(SVPLA(2)), present in the Viperidae snake family exhibit a wide range of toxic and pharmacological effects. They exert their different functions by catalyzing the hydrolysis of phospholipids (PL) at the membrane/water interface and...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248580/ https://www.ncbi.nlm.nih.gov/pubmed/18062812 http://dx.doi.org/10.1186/1472-6807-7-82 |