SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice

Prader-Willi syndrome (PWS) is the leading genetic cause of obesity. After initial severe hypotonia, PWS children become hyperphagic and morbidly obese, if intake is not restricted. Short stature with abnormal growth hormone secretion, hypogonadism, cognitive impairment, anxiety and behavior problem...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Feng, Li, Hong Hua, Zhang, Shengwen, Solomon, Nicola M., Camper, Sally A., Cohen, Pinchas, Francke, Uta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248623/
https://www.ncbi.nlm.nih.gov/pubmed/18320030
http://dx.doi.org/10.1371/journal.pone.0001709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248623/
https://www.ncbi.nlm.nih.gov/pubmed/18320030
http://dx.doi.org/10.1371/journal.pone.0001709

Ejemplares similares