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SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice

Prader-Willi syndrome (PWS) is the leading genetic cause of obesity. After initial severe hypotonia, PWS children become hyperphagic and morbidly obese, if intake is not restricted. Short stature with abnormal growth hormone secretion, hypogonadism, cognitive impairment, anxiety and behavior problem...

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Detalles Bibliográficos
Autores principales:	Ding, Feng, Li, Hong Hua, Zhang, Shengwen, Solomon, Nicola M., Camper, Sally A., Cohen, Pinchas, Francke, Uta
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248623/ https://www.ncbi.nlm.nih.gov/pubmed/18320030 http://dx.doi.org/10.1371/journal.pone.0001709

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