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Troponin and Titin Coordinately Regulate Length-dependent Activation in Skinned Porcine Ventricular Muscle
We investigated the molecular mechanism by which troponin (Tn) regulates the Frank-Starling mechanism of the heart. Quasi-complete reconstitution of thin filaments with rabbit fast skeletal Tn (sTn) attenuated length-dependent activation in skinned porcine left ventricular muscle, to a magnitude sim...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248715/ https://www.ncbi.nlm.nih.gov/pubmed/18299397 http://dx.doi.org/10.1085/jgp.200709895 |