Calmodulin Regulation of Na(V)1.4 Current: Role of Binding to the Carboxyl Terminus

Calmodulin (CaM) regulates steady-state inactivation of sodium currents (Na(V)1.4) in skeletal muscle. Defects in Na current inactivation are associated with pathological muscle conditions such as myotonia and paralysis. The mechanisms of CaM modulation of expression and function of the Na channel a...

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Detalles Bibliográficos
Autores principales: Biswas, Subrata, Deschênes, Isabelle, DiSilvestre, Deborah, Tian, Yanli, Halperin, Victoria L., Tomaselli, Gordon F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248716/
https://www.ncbi.nlm.nih.gov/pubmed/18270170
http://dx.doi.org/10.1085/jgp.200709863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248716/
https://www.ncbi.nlm.nih.gov/pubmed/18270170
http://dx.doi.org/10.1085/jgp.200709863

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