Mapping the phase diagram of the writhe of DNA nanocircles using atomistic molecular dynamics simulations

We have investigated the effects of duplex length, sequence, salt concentration and superhelical density on the conformation of DNA nanocircles containing up to 178 base pairs using atomistic molecular dynamics simulation. These calculations reveal that the partitioning of twist and writhe is govern...

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Detalles Bibliográficos
Autores principales: Harris, Sarah A., Laughton, Charles A., Liverpool, Tanniemola B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248748/
https://www.ncbi.nlm.nih.gov/pubmed/17984075
http://dx.doi.org/10.1093/nar/gkm891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248748/
https://www.ncbi.nlm.nih.gov/pubmed/17984075
http://dx.doi.org/10.1093/nar/gkm891

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