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Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells

Estrogen receptors (ERs), which mediate the proliferative action of estrogens in breast cancer cells, are ligand-dependent transcription factors that regulate expression of their primary target genes through several mechanisms. In addition to direct binding to cognate DNA sequences, ERs can be recru...

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Detalles Bibliográficos
Autores principales: Bourdeau, Véronique, Deschênes, Julie, Laperrière, David, Aid, Malika, White, John H., Mader, Sylvie
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248750/
https://www.ncbi.nlm.nih.gov/pubmed/17986456
http://dx.doi.org/10.1093/nar/gkm945