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Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells
Estrogen receptors (ERs), which mediate the proliferative action of estrogens in breast cancer cells, are ligand-dependent transcription factors that regulate expression of their primary target genes through several mechanisms. In addition to direct binding to cognate DNA sequences, ERs can be recru...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248750/ https://www.ncbi.nlm.nih.gov/pubmed/17986456 http://dx.doi.org/10.1093/nar/gkm945 |