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CpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding

Cell-death-inducing DFF45-like effector A (CIDE-A) belongs to a family of proapoptotic proteins, the expression of which is highly restricted in human tissues and cells. Here, the core region of the human CIDE-A promoter was characterized. Surprisingly, two Sp1/Sp3-binding sites, rather than tissue-...

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Detalles Bibliográficos
Autores principales: Li, Dong, Da, Liang, Tang, Hong, Li, Tsaiping, Zhao, Mujun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248752/
https://www.ncbi.nlm.nih.gov/pubmed/18033804
http://dx.doi.org/10.1093/nar/gkm1028