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In situ oligonucleotide synthesis on carbon materials: stable substrates for microarray fabrication

Glass has become the standard substrate for the preparation of DNA arrays. Typically, glass is modified using silane chemistries to provide an appropriate functional group for nucleic acid synthesis or oligonucleotide immobilization. We have found substantial issues with the stability of these surfa...

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Detalles Bibliográficos
Autores principales: Phillips, Margaret F., Lockett, Matthew R., Rodesch, Matthew J., Shortreed, Michael R., Cerrina, Franco, Smith, Lloyd M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248760/
https://www.ncbi.nlm.nih.gov/pubmed/18084027
http://dx.doi.org/10.1093/nar/gkm1103