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Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis

BACKGROUND: We have recently shown that curcumin (a diferuloylmethane, the yellow pigment in turmeric) enhances apoptosis-inducing potential of TRAIL in prostate cancer PC-3 cells, and sensitizes TRAIL-resistant LNCaP cells in vitro through multiple mechanisms. The objectives of this study were to i...

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Detalles Bibliográficos
Autores principales: Shankar, Sharmila, Ganapathy, Suthakar, Chen, Qinghe, Srivastava, Rakesh K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249593/
https://www.ncbi.nlm.nih.gov/pubmed/18226269
http://dx.doi.org/10.1186/1476-4598-7-16