Maximum likelihood estimates of two-locus recombination fractions under some natural inequality restrictions

BACKGROUND: The goal of linkage analysis is to determine the chromosomal location of the gene(s) for a trait of interest such as a common disease. Three-locus linkage analysis is an important case of multi-locus problems. Solutions can be found analytically for the case of triple backcross mating. H...

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Detalles Bibliográficos
Autores principales: Zhou, Ying, Shi, Ning-Zhong, Fung, Wing-Kam, Guo, Jianhua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249595/
https://www.ncbi.nlm.nih.gov/pubmed/18173855
http://dx.doi.org/10.1186/1471-2156-9-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249595/
https://www.ncbi.nlm.nih.gov/pubmed/18173855
http://dx.doi.org/10.1186/1471-2156-9-1

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