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Maximum likelihood estimates of two-locus recombination fractions under some natural inequality restrictions
BACKGROUND: The goal of linkage analysis is to determine the chromosomal location of the gene(s) for a trait of interest such as a common disease. Three-locus linkage analysis is an important case of multi-locus problems. Solutions can be found analytically for the case of triple backcross mating. H...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249595/ https://www.ncbi.nlm.nih.gov/pubmed/18173855 http://dx.doi.org/10.1186/1471-2156-9-1 |