SOD1 and Amyotrophic Lateral Sclerosis: Mutations and Oligomerization

There are about 100 single point mutations of copper, zinc superoxide dismutase 1 (SOD1) which are reported (http://alsod.iop.kcl.ac.uk/Als/index.aspx) to be related to the familial form (fALS) of amyotrophic lateral sclerosis (ALS). These mutations are spread all over the protein. It is well docume...

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Detalles Bibliográficos
Autores principales: Banci, Lucia, Bertini, Ivano, Boca, Mirela, Girotto, Stefania, Martinelli, Manuele, Valentine, Joan Selverstone, Vieru, Miguela
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2250751/
https://www.ncbi.nlm.nih.gov/pubmed/18301754
http://dx.doi.org/10.1371/journal.pone.0001677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2250751/
https://www.ncbi.nlm.nih.gov/pubmed/18301754
http://dx.doi.org/10.1371/journal.pone.0001677

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