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IdeS: A Bacterial Proteolytic Enzyme with Therapeutic Potential

BACKGROUND: IdeS, a proteinase from Streptococcus pyogenes, cleaves immunoglobulin (Ig)G antibodies with a unique degree of specificity. Pathogenic IgG antibodies constitute an important clinical problem contributing to the pathogenesis of a number of autoimmune conditions and acute transplant rejec...

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Detalles Bibliográficos
Autores principales: Johansson, Björn P., Shannon, Oonagh, Björck, Lars
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253494/
https://www.ncbi.nlm.nih.gov/pubmed/18301769
http://dx.doi.org/10.1371/journal.pone.0001692