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Tula hantavirus isolate with the full-length ORF for nonstructural protein NSs survives for more consequent passages in interferon-competent cells than the isolate having truncated NSs ORF

BACKGROUND: The competitiveness of two Tula hantavirus (TULV) isolates, TULV/Lodz and TULV/Moravia, was evaluated in interferon (IFN) -competent and IFN-deficient cells. The two isolates differ in the length of the open reading frame (ORF) encoding the nonstructural protein NSs, which has previously...

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Detalles Bibliográficos
Autores principales: Jääskeläinen, Kirsi M, Plyusnina, Angelina, Lundkvist, Åke, Vaheri, Antti, Plyusnin, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253529/
https://www.ncbi.nlm.nih.gov/pubmed/18190677
http://dx.doi.org/10.1186/1743-422X-5-3