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Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration

BACKGROUND: Meta-analyses of antidepressant medications have reported only modest benefits over placebo treatment, and when unpublished trial data are included, the benefit falls below accepted criteria for clinical significance. Yet, the efficacy of the antidepressants may also depend on the severi...

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Detalles Bibliográficos
Autores principales: Kirsch, Irving, Deacon, Brett J, Huedo-Medina, Tania B, Scoboria, Alan, Moore, Thomas J, Johnson, Blair T
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253608/
https://www.ncbi.nlm.nih.gov/pubmed/18303940
http://dx.doi.org/10.1371/journal.pmed.0050045