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Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration
BACKGROUND: Meta-analyses of antidepressant medications have reported only modest benefits over placebo treatment, and when unpublished trial data are included, the benefit falls below accepted criteria for clinical significance. Yet, the efficacy of the antidepressants may also depend on the severi...
Autores principales: | Kirsch, Irving, Deacon, Brett J, Huedo-Medina, Tania B, Scoboria, Alan, Moore, Thomas J, Johnson, Blair T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253608/ https://www.ncbi.nlm.nih.gov/pubmed/18303940 http://dx.doi.org/10.1371/journal.pmed.0050045 |
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