T Cell Receptor Engagement Triggers Its CD3ε and CD3ζ Subunits to Adopt a Compact, Locked Conformation

How the T cell antigen receptor (TCR) discriminates between molecularly related peptide/Major Histocompatibility Complex (pMHC) ligands and converts this information into different possible signaling outcomes is still not understood. One current model proposes that strong pMHC ligands, but not weak...

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Detalles Bibliográficos
Autores principales: Risueño, Ruth M., Schamel, Wolfgang W. A., Alarcón, Balbino
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254190/
https://www.ncbi.nlm.nih.gov/pubmed/18320063
http://dx.doi.org/10.1371/journal.pone.0001747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254190/
https://www.ncbi.nlm.nih.gov/pubmed/18320063
http://dx.doi.org/10.1371/journal.pone.0001747

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