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T Cell Receptor Engagement Triggers Its CD3ε and CD3ζ Subunits to Adopt a Compact, Locked Conformation

How the T cell antigen receptor (TCR) discriminates between molecularly related peptide/Major Histocompatibility Complex (pMHC) ligands and converts this information into different possible signaling outcomes is still not understood. One current model proposes that strong pMHC ligands, but not weak...

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Detalles Bibliográficos
Autores principales:	Risueño, Ruth M., Schamel, Wolfgang W. A., Alarcón, Balbino
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254190/ https://www.ncbi.nlm.nih.gov/pubmed/18320063 http://dx.doi.org/10.1371/journal.pone.0001747

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