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Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas

BACKGROUND: The prognosis for malignant gliomas remains dismal. We addressed the safety, feasibility and preliminary clinical activity of the vaccinations using autologous glioma cells and interleukin (IL)-4 gene transfected fibroblasts. METHODS: In University of Pittsburgh Cancer Institute (UPCI) p...

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Detalles Bibliográficos
Autores principales: Okada, Hideho, Lieberman, Frank S, Walter, Kevin A, Lunsford, L Dade, Kondziolka, Douglas S, Bejjani, Ghassan K, Hamilton, Ronald L, Torres-Trejo, Alejandro, Kalinski, Pawel, Cai, Quan, Mabold, Jennifer L, Edington, Howard D, Butterfield, Lisa H, Whiteside, Theresa L, Potter, Douglas M, Schold, S Clifford, Pollack, Ian F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254376/
https://www.ncbi.nlm.nih.gov/pubmed/18093335
http://dx.doi.org/10.1186/1479-5876-5-67