Evaluating dose response from flexible dose clinical trials

BACKGROUND: The true dose effect in flexible-dose clinical trials may be obscured and even reversed because dose and outcome are related. METHODS: To evaluate dose effect in response on primary efficacy scales from 2 randomized, double-blind, flexible-dose trials of patients with bipolar mania who r...

Descripción completa

Detalles Bibliográficos
Autores principales: Lipkovich, Ilya, Adams, David H, Mallinckrodt, Craig, Faries, Doug, Baron, David, Houston, John P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254403/
https://www.ncbi.nlm.nih.gov/pubmed/18179713
http://dx.doi.org/10.1186/1471-244X-8-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254403/
https://www.ncbi.nlm.nih.gov/pubmed/18179713
http://dx.doi.org/10.1186/1471-244X-8-3

Ejemplares similares