Cargando…
Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2
BACKGROUND: Wnt signaling is mediated through 1) the beta-catenin dependent canonical pathway and, 2) the beta-catenin independent pathways. Multiple receptors, including Fzds, Lrps, Ror2 and Ryk, are involved in Wnt signaling. Ror2 is a single-span transmembrane receptor-tyrosine kinase (RTK). The...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254434/ https://www.ncbi.nlm.nih.gov/pubmed/18215320 http://dx.doi.org/10.1186/1471-2199-9-11 |