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CD39, NTPDase 1, is attached to the plasma membrane by two transmembrane domains. Why?

Since the identification of CD39 and other members of the e-NTPDase (ecto-nucleoside triphosphate diphosphohydrolase) family as the primary enzymes responsible for cell surface nucleotide hydrolysis, one of their most intriguing features has been their unusual topology. The active site lies in the l...

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Detalles Bibliográficos
Autores principales: Grinthal, Alison, Guidotti, Guido
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254477/
https://www.ncbi.nlm.nih.gov/pubmed/18404478
http://dx.doi.org/10.1007/s11302-005-5907-8