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Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction

BACKGROUND: The hepatocyte growth factor (HGF) stimulates mitogenesis, motogenesis, and morphogenesis in a wide range of tissues, including epithelial cells, on binding to the receptor tyrosine kinase c-Met. Abnormal c-Met signalling contributes to tumour genesis, in particular to the development of...

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Detalles Bibliográficos
Autores principales: Franke, Raimo, Müller, Melanie, Wundrack, Nicole, Gilles, Ernst-Dieter, Klamt, Steffen, Kähne, Thilo, Naumann, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254585/
https://www.ncbi.nlm.nih.gov/pubmed/18194572
http://dx.doi.org/10.1186/1752-0509-2-4