Cargando…
Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction
BACKGROUND: The hepatocyte growth factor (HGF) stimulates mitogenesis, motogenesis, and morphogenesis in a wide range of tissues, including epithelial cells, on binding to the receptor tyrosine kinase c-Met. Abnormal c-Met signalling contributes to tumour genesis, in particular to the development of...
Autores principales: | Franke, Raimo, Müller, Melanie, Wundrack, Nicole, Gilles, Ernst-Dieter, Klamt, Steffen, Kähne, Thilo, Naumann, Michael |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254585/ https://www.ncbi.nlm.nih.gov/pubmed/18194572 http://dx.doi.org/10.1186/1752-0509-2-4 |
Ejemplares similares
-
Logical network of genotoxic stress-induced NF-κB signal transduction predicts putative target structures for therapeutic intervention strategies
por: Poltz, Rainer, et al.
Publicado: (2009) -
Interactome analysis of transforming growth factor-β-activated kinase 1 in Helicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37
por: Sokolova, Olga, et al.
Publicado: (2018) -
Visual setup of logical models of signaling and regulatory networks with ProMoT
por: Saez-Rodriguez, Julio, et al.
Publicado: (2006) -
The Versatility of the Helicobacter pylori Vacuolating Cytotoxin VacA in Signal Transduction and Molecular Crosstalk
por: Backert, Steffen, et al.
Publicado: (2010) -
Helicobacter pylori-Mediated Immunity and Signaling Transduction in Gastric Cancer
por: Ito, Nozomi, et al.
Publicado: (2020)