Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt

BACKGROUND: Previous studies have suggested that peroxisome proliferator activated receptor-gamma (PPAR-γ)-mediated neuroprotection involves inhibition of microglial activation and decreased expression and activity of inducible nitric oxide synthase (iNOS); however, the underlying molecular mechanis...

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Detalles Bibliográficos
Autores principales: Xing, Bin, Xin, Tao, Hunter, Randy Lee, Bing, Guoying
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254610/
https://www.ncbi.nlm.nih.gov/pubmed/18205920
http://dx.doi.org/10.1186/1742-2094-5-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254610/
https://www.ncbi.nlm.nih.gov/pubmed/18205920
http://dx.doi.org/10.1186/1742-2094-5-4

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