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Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt

BACKGROUND: Previous studies have suggested that peroxisome proliferator activated receptor-gamma (PPAR-γ)-mediated neuroprotection involves inhibition of microglial activation and decreased expression and activity of inducible nitric oxide synthase (iNOS); however, the underlying molecular mechanis...

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Detalles Bibliográficos
Autores principales:	Xing, Bin, Xin, Tao, Hunter, Randy Lee, Bing, Guoying
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254610/ https://www.ncbi.nlm.nih.gov/pubmed/18205920 http://dx.doi.org/10.1186/1742-2094-5-4

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