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The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1
BACKGROUND: The mechanism by which Hsp40 and other molecular chaperones recognize and interact with non-native polypeptides is a fundamental question. How Hsp40 co-operates with Hsp70 to facilitate protein folding is not well understood. To investigate the mechanisms, we determined the crystal struc...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254625/ https://www.ncbi.nlm.nih.gov/pubmed/18211704 http://dx.doi.org/10.1186/1472-6807-8-3 |