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The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1

BACKGROUND: The mechanism by which Hsp40 and other molecular chaperones recognize and interact with non-native polypeptides is a fundamental question. How Hsp40 co-operates with Hsp70 to facilitate protein folding is not well understood. To investigate the mechanisms, we determined the crystal struc...

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Detalles Bibliográficos
Autores principales: Hu, Junbin, Wu, Yunkun, Li, Jingzhi, Qian, Xinguo, Fu, Zhengqing, Sha, Bingdong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254625/
https://www.ncbi.nlm.nih.gov/pubmed/18211704
http://dx.doi.org/10.1186/1472-6807-8-3