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Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse

BACKGROUND: The hypogonadal (hpg) mouse is widely used as an animal model with which to investigate the endocrine regulation of spermatogenesis. Chronic treatment of these GnRH-deficient mice with estradiol is known to induce testicular maturation and restore qualitatively normal spermatogenesis. Th...

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Detalles Bibliográficos
Autores principales: Baines, Helen, Nwagwu, Margaret O, Hastie, Graham R, Wiles, Roman A, Mayhew, Terry M, Ebling, Francis JP
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254628/
https://www.ncbi.nlm.nih.gov/pubmed/18230131
http://dx.doi.org/10.1186/1477-7827-6-4