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Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk
BACKGROUND: Estrogens are crucial tumorigenic hormones, which impact the cell growth and proliferation during breast cancer development. Estrogens are metabolized by a series of enzymes including COMT, which converts catechol estrogens into biologically non-hazardous methoxyestrogens. Several studie...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254632/ https://www.ncbi.nlm.nih.gov/pubmed/18194538 http://dx.doi.org/10.1186/1471-2407-8-6 |