Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk

BACKGROUND: Estrogens are crucial tumorigenic hormones, which impact the cell growth and proliferation during breast cancer development. Estrogens are metabolized by a series of enzymes including COMT, which converts catechol estrogens into biologically non-hazardous methoxyestrogens. Several studie...

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Detalles Bibliográficos
Autores principales: Onay, Ummiye V, Aaltonen, Kirsimari, Briollais, Laurent, Knight, Julia A, Pabalan, Noel, Kilpivaara, Outi, Andrulis, Irene L, Blomqvist, Carl, Nevanlinna, Heli, Ozcelik, Hilmi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254632/
https://www.ncbi.nlm.nih.gov/pubmed/18194538
http://dx.doi.org/10.1186/1471-2407-8-6

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