IgE alone promotes human lung mast cell survival through the autocrine production of IL-6

BACKGROUND: Mast cells play a key role in asthma and recent evidence indicates that their ongoing activation in this disease is mediated, in part, via IgE in the absence of antigen. In this study we have examined whether IgE alone enhances human lung mast cell (HLMC) survival. METHODS: Purified HLMC...

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Detalles Bibliográficos
Autores principales: Cruse, Glenn, Cockerill, Sarah, Bradding, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257927/
https://www.ncbi.nlm.nih.gov/pubmed/18215266
http://dx.doi.org/10.1186/1471-2172-9-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257927/
https://www.ncbi.nlm.nih.gov/pubmed/18215266
http://dx.doi.org/10.1186/1471-2172-9-2

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