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Substrate specificity of new methyl-directed DNA endonuclease GlaI

BACKGROUND: Recently, we have discovered site-specific endonucleases, which recognize and cleave only DNA sequences with 5-methylcytosine. Two specificities of such endonucleases have been described. Enzymes BisI, BlsI, and GluI are isoschizomers and hydrolyze the DNA sequence 5'-GCNGC-3'/...

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Detalles Bibliográficos
Autores principales: Tarasova, Galina V, Nayakshina, Tatiana N, Degtyarev, Sergey KH
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257971/
https://www.ncbi.nlm.nih.gov/pubmed/18194583
http://dx.doi.org/10.1186/1471-2199-9-7