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Substrate specificity of new methyl-directed DNA endonuclease GlaI
BACKGROUND: Recently, we have discovered site-specific endonucleases, which recognize and cleave only DNA sequences with 5-methylcytosine. Two specificities of such endonucleases have been described. Enzymes BisI, BlsI, and GluI are isoschizomers and hydrolyze the DNA sequence 5'-GCNGC-3'/...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257971/ https://www.ncbi.nlm.nih.gov/pubmed/18194583 http://dx.doi.org/10.1186/1471-2199-9-7 |