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Open-Label Comparative Clinical Study of Chlorproguanil−Dapsone Fixed Dose Combination (Lapdap™) Alone or with Three Different Doses of Artesunate for Uncomplicated Plasmodium falciparum Malaria

The objective of this study was to determine the appropriate dose of artesunate for use in a fixed dose combination therapy with chlorproguanil−dapsone (CPG−DDS) for the treatment of uncomplicated falciparum malaria. METHODS: Open-label clinical trial comparing CPG−DDS alone or with artesunate 4, 2,...

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Detalles Bibliográficos
Autores principales: Wootton, Daniel G., Opara, Hyginus, Biagini, Giancarlo A., Kanjala, Maxwell K., Duparc, Stephan, Kirby, Paula L., Woessner, Mary, Neate, Colin, Nyirenda, Maggie, Blencowe, Hannah, Dube-Mbeye, Queen, Kanyok, Thomas, Ward, Stephen, Molyneux, Malcolm, Dunyo, Sam, Winstanley, Peter A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258152/
https://www.ncbi.nlm.nih.gov/pubmed/18320064
http://dx.doi.org/10.1371/journal.pone.0001779