Determinants of protein function revealed by combinatorial entropy optimization

We use a new algorithm (combinatorial entropy optimization [CEO]) to identify specificity residues and functional subfamilies in sets of proteins related by evolution. Specificity residues are conserved within a subfamily but differ between subfamilies, and they typically encode functional diversity...

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Detalles Bibliográficos
Autores principales: Reva, Boris, Antipin, Yevgeniy, Sander, Chris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258190/
https://www.ncbi.nlm.nih.gov/pubmed/17976239
http://dx.doi.org/10.1186/gb-2007-8-11-r232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258190/
https://www.ncbi.nlm.nih.gov/pubmed/17976239
http://dx.doi.org/10.1186/gb-2007-8-11-r232

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