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Predicting biological system objectives de novo from internal state measurements

BACKGROUND: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For example, methods are emerging to engineer cells to optimally produce byproducts of commercial value, such as bioethanol, as we...

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Detalles Bibliográficos
Autores principales: Gianchandani, Erwin P, Oberhardt, Matthew A, Burgard, Anthony P, Maranas, Costas D, Papin, Jason A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258290/
https://www.ncbi.nlm.nih.gov/pubmed/18218092
http://dx.doi.org/10.1186/1471-2105-9-43