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Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons

Cohesin is a highly conserved multisubunit complex that holds sister chromatids together in mitotic cells. At the metaphase to anaphase transition, proteolytic cleavage of the α kleisin subunit (Rad21) by separase causes cohesin's dissociation from chromosomes and triggers sister-chromatid disj...

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Detalles Bibliográficos
Autores principales: Pauli, Andrea, Althoff, Friederike, Oliveira, Raquel A., Heidmann, Stefan, Schuldiner, Oren, Lehner, Christian F., Dickson, Barry J., Nasmyth, Kim
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258333/
https://www.ncbi.nlm.nih.gov/pubmed/18267092
http://dx.doi.org/10.1016/j.devcel.2007.12.009