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Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons
Cohesin is a highly conserved multisubunit complex that holds sister chromatids together in mitotic cells. At the metaphase to anaphase transition, proteolytic cleavage of the α kleisin subunit (Rad21) by separase causes cohesin's dissociation from chromosomes and triggers sister-chromatid disj...
Autores principales: | Pauli, Andrea, Althoff, Friederike, Oliveira, Raquel A., Heidmann, Stefan, Schuldiner, Oren, Lehner, Christian F., Dickson, Barry J., Nasmyth, Kim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258333/ https://www.ncbi.nlm.nih.gov/pubmed/18267092 http://dx.doi.org/10.1016/j.devcel.2007.12.009 |
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