Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content

BACKGROUND: The frequency of synonymous codon usage varies widely between organisms. Suboptimal codon content limits expression of viral, experimental or therapeutic heterologous proteins due to limiting cognate tRNAs. Codon content is therefore often adjusted to match codon bias of the host organis...

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Detalles Bibliográficos
Autores principales: Robinson, Fiona, Jackson, Richard J., Smith, Christopher W. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258417/
https://www.ncbi.nlm.nih.gov/pubmed/18335065
http://dx.doi.org/10.1371/journal.pone.0001801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258417/
https://www.ncbi.nlm.nih.gov/pubmed/18335065
http://dx.doi.org/10.1371/journal.pone.0001801

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