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The Orexigenic Effect of Ghrelin Is Mediated through Central Activation of the Endogenous Cannabinoid System

INTRODUCTION: Ghrelin and cannabinoids stimulate appetite, this effect possibly being mediated by the activation of hypothalamic AMP-activated protein kinase (AMPK), a key enzyme in appetite and metabolism regulation. The cannabinoid receptor type 1 (CB1) antagonist rimonabant can block the orexigen...

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Detalles Bibliográficos
Autores principales: Kola, Blerina, Farkas, Imre, Christ-Crain, Mirjam, Wittmann, Gábor, Lolli, Francesca, Amin, Faisal, Harvey-White, Judith, Liposits, Zsolt, Kunos, George, Grossman, Ashley B., Fekete, Csaba, Korbonits, Márta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258435/
https://www.ncbi.nlm.nih.gov/pubmed/18335063
http://dx.doi.org/10.1371/journal.pone.0001797