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CD44(+)CD24(−) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis

Recent evidence supports the hypothesis that cancer stem cells are responsible for tumour initiation and formation. Using flow cytometry, we isolated a population of CD44(+)CD24(−) prostate cells that display stem cell characteristics as well as gene expression patterns that predict overall survival...

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Detalles Bibliográficos
Autores principales: Hurt, E M, Kawasaki, B T, Klarmann, G J, Thomas, S B, Farrar, W L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259168/
https://www.ncbi.nlm.nih.gov/pubmed/18268494
http://dx.doi.org/10.1038/sj.bjc.6604242