Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status

The expression and activity of the epidermal growth factor receptor (EGFR) are determinants of radiosensitivity in several tumour types, including non-small cell lung cancer (NSCLC). However, little is known of whether genetic alterations of EGFR in NSCLC cells affect the therapeutic response to mon...

Descripción completa

Detalles Bibliográficos
Autores principales: Akashi, Y, Okamoto, I, Iwasa, T, Yoshida, T, Suzuki, M, Hatashita, E, Yamada, Y, Satoh, T, Fukuoka, M, Ono, K, Nakagawa, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259177/
https://www.ncbi.nlm.nih.gov/pubmed/18253126
http://dx.doi.org/10.1038/sj.bjc.6604222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259177/
https://www.ncbi.nlm.nih.gov/pubmed/18253126
http://dx.doi.org/10.1038/sj.bjc.6604222

Ejemplares similares