SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis

SOX transcription factors are essential for embryonic development and play critical roles in cell fate determination, differentiation and proliferation. We previously reported that the SOX2 protein is expressed in normal gastric mucosae but downregulated in some human gastric carcinomas. To clarify...

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Detalles Bibliográficos
Autores principales: Otsubo, T, Akiyama, Y, Yanagihara, K, Yuasa, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259184/
https://www.ncbi.nlm.nih.gov/pubmed/18268498
http://dx.doi.org/10.1038/sj.bjc.6604193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259184/
https://www.ncbi.nlm.nih.gov/pubmed/18268498
http://dx.doi.org/10.1038/sj.bjc.6604193

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