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Targeting telomerase for cancer therapeutics

One of the hallmarks of advanced malignancies is continuous cell growth and this almost universally correlates with the reactivation of telomerase. Although there is still much we do not understand about the regulation of telomerase, it remains a very attractive and novel target for cancer therapeut...

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Detalles Bibliográficos
Autores principales: Shay, J W, Keith, W N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259186/
https://www.ncbi.nlm.nih.gov/pubmed/18231105
http://dx.doi.org/10.1038/sj.bjc.6604209