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Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships

BACKGROUND: The neprilysin (M13) family of endopeptidases are zinc-metalloenzymes, the majority of which are type II integral membrane proteins. The best characterised of this family is neprilysin, which has important roles in inactivating signalling peptides involved in modulating neuronal activity...

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Detalles Bibliográficos
Autores principales: Bland, Nicholas D, Pinney, John W, Thomas, Josie E, Turner, Anthony J, Isaac, R Elwyn
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259306/
https://www.ncbi.nlm.nih.gov/pubmed/18215274
http://dx.doi.org/10.1186/1471-2148-8-16